Varcogroups

Effervescent Tablets Line

Effervescent tablets are easy to consume due to this they are getting popular over other oral dosage forms. Effervescent tablets get break when they are put in water or juice which causes tablet to dissolve and form a solution. USFDA redefined the definition to Effervescent tablet is a tablet intended to be dissolved or dispersed in water before administration. Effervescent tablets consists of acids/acid salt, carbonates and hydrogen carbonates, flavour, sweetener, etc. which release carbon dioxide when it is added to water. Following chemical reaction takes place in effervescent tablets. C6H8O7 (aq) + 3NaHCO3 (aq) → Na3C6H5O7 (aq) + 4H2O + 3CO2 (g) ↑ Citric acid + Sodium bicarbonate → Sodium citrate + Water + Carbon dioxide

The above reaction occurs due to presence of water, because water is one of the reaction product which accelerates the reaction, leading to difficulty in stopping the reaction. Due to this reason manufacturing and storage of effervescent product is planned by minimizing their contact with water [2,3].

Advantages of Effervescent Tablets

Limitations of Effervescent Tablets

Excipients Used of Effervescent Tablets

Acids

• Citric acid
• Tartaric acid
• Adipic acid
• Fumaric acid
• Malic acid

Carbonates/Bicarbonates

• Sodium carbonate
• Potassium carbonate
• Calcium carbonate
• Sodium bicarbonate
• Potassium bicarbonate

Lubricants

• Sodium benzoate
• Polyethylene glycol
• Adipic acid
• Magnesium stearate

Inders

• Lactose
• Sorbitol
• Xylitol
• Dextrose

Sweeteners

• Acesulfame potassium
• Sodium saccharin
• Aspartame
• Sucralose

Flavours

• Powdarome Lemon
• Powdarome Orange
• Strawberry Flavour
• Tutti Frutti Flavo

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