Varcogroups

EFFERVESCENT
TABLETS LINE

Our Product Range

Effervescent Tablets Line

Effervescent tablets are easy to consume due to this they are getting popular over other oral dosage forms. Effervescent tablets get break when they are put in water or juice which causes tablet to dissolve and form a solution. USFDA redefined the definition to Effervescent tablet is a tablet intended to be dissolved or dispersed in water before administration. Effervescent tablets consists of acids/acid salt, carbonates and hydrogen carbonates, flavour, sweetener, etc. which release carbon dioxide when it is added to water. Following chemical reaction takes place in effervescent tablets. C6H8O7 (aq) + 3NaHCO3 (aq) → Na3C6H5O7 (aq) + 4H2O + 3CO2 (g) ↑ Citric acid + Sodium bicarbonate → Sodium citrate + Water + Carbon dioxide

The above reaction occurs due to presence of water, because water is one of the reaction product which accelerates the reaction, leading to difficulty in stopping the reaction. Due to this reason manufacturing and storage of effervescent product is planned by minimizing their contact with water [2,3].

Advantages of Effervescent Tablets Limitations of Effervescent Tablets
Administered as palatable sparkling solution Excipients are costly
Readily absorbed because it has to be consumed in solution form Special production facilities are required
No need to swallow tablet High sodium or potassium makes it inappropriate for patients with heart failure or cardiac insufficiency
Drugs that are unstable in aqueous solution when stored show more stable state in effervescent granules or tablet forms Difficult to formulate drugs with unpleasant taste sufficiently palatable as an effervescent product
Better/good intestinal and stomach tolerance
Large amount of active ingredients can be easily incorporated
Better or accurate dosing
Rapid onset of action
Good in taste
Category Examples
Acids • Citric acid • Tartaric acid • Adipic acid • Fumaric acid • Malic acid
Carbonates/Bicarbonates • Sodium carbonate • Potassium carbonate • Calcium carbonate • Sodium bicarbonate • Potassium bicarbonate
Lubricants • Sodium benzoate • Polyethylene glycol • Adipic acid • Magnesium stearate
Inders • Lactose • Sorbitol • Xylitol • Dextrose
Sweeteners • Acesulfame potassium • Sodium saccharin • Aspartame • Sucralose
Flavours • Powdarome Lemon • Powdarome Orange • Strawberry Flavour • Tutti Frutti Flavour

Product Features

1
The production line typically starts with a mixing and blending unit where the active pharmaceutical ingredients (APIs), excipients, and flavoring agents are mixed together to form a homogenous blend.
2
In some cases, the blended powder may undergo granulation to improve flow properties and compressibility. Wet granulation or dry granulation techniques may be used depending on the formulation.
3
The granulated powder blend is then fed into tablet presses where it is compressed into effervescent tablets of the desired shape, size, and weight. Rotary or single-punch tablet presses are commonly used in this process.
4
After compression, effervescent tablets may undergo a coating process to improve stability, taste, and appearance. Coating can also provide enteric protection or modify the release characteristics of the tablet.
5
If the coating process involves the use of aqueous solutions, the coated tablets may need to be dried to remove excess moisture and ensure proper coating adhesion.
6
The final step in the production line involves packaging the effervescent tablets into blister packs, bottles, or sachets. Automated packaging equipment is used to accurately fill and seal the packaging containers.

Why Global Companies Trust Varcotech Equipment Pvt Ltd

Top Quality Factory Price

We have a quality control department to verify each product at different phases, from the procurement of parts to finished products

As Your Layout, Customize Machine

According to your layout, we can suggest the best capacity and type for you, customize equipment for you

Equipment Consult & Design Service

Save energy resource for you, professional engineers can improve the best processing solution. We have the experience to help add a tremendous amount of value to your project

ISO.CE Standard Qualified

We successfully obtaining the ISO9001:2008 certificate and CE security management system certificate, this is significant for Senieer in building enterprise image

Equipment Training & Maintance Service

Free Equipment training & maintenance service for you, we will provide your team in-depth training on safe operation and equipment maintenance

Equipment Installation Service

Varco Groups offers equipment installation & commissioning service for production products, your equipment and control systems are qualified based on the GAMP life-cycle

Contact Varcotech equipment pvt ltd Team
error: Content is protected !!